Application
Sample (30 ug of whole cell lysate) A: Raji B: K562 5% SDS PAGE diluted at 1:1000Application
CD89 antibody detects CD89 protein at cytoplasm in human cervical carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human cervical carcinoma. CD89 antibody diluted at 1:500.| Product Name | CD89 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CD89 (Fc fragment of IgA, receptor for)This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human CD89. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
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| Species Reactivity | Human |
| Predicted Reactivity | Rhesus Monkey, ChimpanzeeRhesus Monkey (92%), Chimpanzee (93%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | CD89 antibody FCAR antibody immunoglobulin alpha Fc receptor antibody Fc alpha receptor antibody IgA Fc receptor antibody "Fc fragment of IgA receptor for antibody" |
|---|---|
| Molecular Weight(MW) | 32 kDa (note) (4) |
| Cellular Localization | Isoform A , 1: Cell membrane; Single-pass type I membrane protein , 2: Cell membrane; Single-pass type I membrane protein , 3: Cell membrane; Single-pass type I membrane protein , Isoform B: Secreted , Isoform B-delta-S2: Secreted |
Application
Sample (30 ug of whole cell lysate) A: Raji B: K562 5% SDS PAGE diluted at 1:1000
Application
CD89 antibody detects CD89 protein at cytoplasm in human cervical carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human cervical carcinoma. CD89 antibody diluted at 1:500.| Positive Control | Raji , K562 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
