Application
Sample (50 ug of whole cell lysate) A: mouse brain 5% SDS PAGE diluted at 1:1000Application
Immunohistochemical analysis of paraffin-embedded human normal lung, using OB-cadherin antibody at 1:250 dilution.| Product Name | CDH11 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to OB-cadherin (cadherin 11, type 2, OB-cadherin (osteoblast))This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human CDH11. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | HumanMouse |
| Predicted Reactivity | Rat, Zebrafish, Xenopus laevis, Pig, Chicken, Rhesus Monkey, BovineRat (100%), Zebrafish (82%), Xenopus laevis (92%), Pig (99%), Chicken (96%), Rhesus Monkey (99%), Bovine (100%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CAD11 antibody CDHOB antibody OB antibody OSF-4 antibody CDH11 antibody cadherin-11 antibody "cadherin 11 type 2 OB-cadherin (osteoblast) antibody" |
|---|---|
| Molecular Weight(MW) | 88 kDa (note) (2) |
| Cellular Localization | Cell membrane |
Application
Sample (50 ug of whole cell lysate) A: mouse brain 5% SDS PAGE diluted at 1:1000
Application
Immunohistochemical analysis of paraffin-embedded human normal lung, using OB-cadherin antibody at 1:250 dilution.| Positive Control | mouse brain |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
