Rabbit Polyclonal antibody to CDH11This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant protein of human CDH11
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCIHC-PWB
WB: 1:500 - 1:2000. IHC: 1:50 - 1:100:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
OSF4 OB CDHOB cadherin 11 CAD11
Target
CDH11
Application
Application
Western blot analysis of extract of various cells, using CDH11 antibody.
Application
Immunohistochemistry of paraffin-embedded mouse brain using CDH11 antibody at dilution of 1:100 (40x lens).