Application
Western blot analysis of c-Met (pY1349) expression in A431 (A); HepG2 (B) whole cell lysates.| Product Name | c-Met (phospho Tyr1349) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to c-Met (phospho Tyr1349)The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human c-Met (pY1349). The exact sequence is proprietary. |
| Modification | p-Tyr1349 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | MET DFNB97 HGFR RCCP2 c-Met MET proto-oncogene receptor tyrosine kinase AUTS9 |
|---|---|
| Target | c-Met |
| Tissue Specificity | Recognizes endogenous levels of c-Met (pY1349) protein. |
Application
Western blot analysis of c-Met (pY1349) expression in A431 (A); HepG2 (B) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 C. Upon delivery aliquot and store at -20 C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. |
