Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Myb (Phospho-Ser532) antibody. The picture on the right is treated with the synthesized peptide.
Rabbit Polyclonal antibody to c-Myb (phospho Ser532)This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009]
Immunogen
Peptide sequence around phosphorylation site of serine 532 (V-E-S(p)-P-T) derived from Human Myb.
Modification
p-Ser532
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-P
IHC: 1:50 - 1:100:
Species Reactivity
HumanMouse
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
The antibody detects endogenous levels of Myb only when phosphorylated at serine 532.
Application
Application
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Myb (Phospho-Ser532) antibody. The picture on the right is treated with the synthesized peptide.
Application Notes
IHC: 1:50 - 1:100:
Additional Information
Form
Liquid
Storage Instructions
Store at -20˚C
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.