Application
Western blot analysis of CD142 (pS290) expression in human kidney (A); human brain (B) whole cell lysates.| Product Name | Coagulation factor III/Tissue factor (phospho Ser290) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Coagulation factor III / Tissue factor (phospho Ser290)This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD142 (pS290). The exact sequence is proprietary. |
| Modification | p-Ser290 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | TF coagulation factor III (thromboplastin tissue factor) F3 CD142 TFA |
|---|---|
| Target | Coagulation factor III / Tissue factor |
| Tissue Specificity | Recognizes endogenous levels of CD142 (pS290) protein. |
Application
Western blot analysis of CD142 (pS290) expression in human kidney (A); human brain (B) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 C. Upon delivery aliquot and store at -20 C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. |
