Rabbit polyclonal antibody to COG2 (component of oligomeric golgi complex 2)This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes. Mutations of this gene are associated with abnormal glycosylation within the Golgi apparatus. Alternative splicing results in multiple transcript variants.
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human COG2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Zebrafish, BovineMouse (94%), Rat (93%), Zebrafish (82%), Bovine (96%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
LDLC antibody COG2 antibody COG complex subunit 2 antibody conserved oligomeric Golgi complex subunit 2 antibody low density lipoprotein receptor defect C complementing antibody "brefeldin A-sensitive peripheral Golgi protein antibody" low density l
Target
COG2
Molecular Weight(MW)
83 kDa (note) (3)
Cellular Localization
Golgi apparatus membrane
Application
Application
Sample (30 ug of whole cell lysate) A: JurKat 7.5% SDS PAGE diluted at 1:1000
Positive Control
Jurkat , Raji
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.