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COL6A1 antibody , Internal

Catalog Number:OM247746
OM247746
Discount Price
OM247746-100ul
1~2 Week
100ul
OM247746-50ul
50ul
OM247746-20ul
20ul
1~2 Week
Product Profile
Product Name COL6A1 antibody , Internal
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to COL6A1 (collagen, type VI, alpha 1)The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq]
Immunogen Recombinant protein encompassing a sequence within the center region of human COL6A1. The exact sequence is proprietary.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity HumanMouse
Predicted Reactivity BovineBovine (87%)
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified
Target Information
Gene Synonyms OPLL antibody
COL6A1 antibody
collagen VI
alpha-1 polypeptide antibody
alpha 1 (VI) chain (61 AA) antibody
collagen alpha-1(VI) chain antibody
collagen
type VI
alpha 1 antibody
Molecular Weight(MW) 109 kDa (note)
Cellular Localization Secreted , extracellular space , extracellular matrix
Application

Application

Sample (50 ug of whole cell lysate) A: Mouse brain 5% SDS PAGE diluted at 1:500

Application

COL6A1 antibody [C1C2], Internal detects COL6A1 protein at cytosol on human hepatoma by immunohistochemical analysis. Sample: Paraffin-embedded hepatoma. COL6A1 antibody [C1C2], Internal dilution: 1:500.

Application

COL6A1 antibody [C1C2], Internal detects COL6A1 protein at cytosol on mouse liver by immunohistochemical analysis. Sample: Paraffin-embedded mouse liver. COL6A1 antibody [C1C2], Internal dilution: 1:500.
Positive Control Mouse brain
Application Notes *Optimal dilutions/concentrations should be determined by the researcher. :
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
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