Rabbit Polyclonal antibody to COL6A1 (collagen, type VI, alpha 1)The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human COL6A1. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Mouse
Predicted Reactivity
Human, BovineHuman (100%), Bovine (95%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
OPLL antibody COL6A1 antibody "collagen VI alpha-1 polypeptide antibody" alpha 1 (VI) chain (61 AA) antibody collagen alpha-1(VI) chain antibody "collagen type VI alpha 1 antibody"
Molecular Weight(MW)
109 kDa (note)
Cellular Localization
Secreted , extracellular space , extracellular matrix
Application
Application
Sample (30 ug of whole cell lysate) A: BCL-1 5% SDS PAGE diluted at 1:500
Positive Control
BCL-1
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.