| Product Name | Collagen alpha-4(IV) antibody , C-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Collagen alpha-4(IV) (collagen, type IV, alpha 4)This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. This particular collagen IV subunit, however, is only found in a subset of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Mutations in this gene are associated with type II autosomal recessive Alport syndrome (hereditary glomerulonephropathy) and with familial benign hematuria (thin basement membrane disease). Two transcripts, differing only in their transcription start sites, have been identified for this gene and, as is common for collagen genes, multiple polyadenylation sites are found in the 3' UTR. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human Collagen alpha-4(IV). The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
|
| Predicted Reactivity | Human, Mouse, DogHuman (100%), Mouse (94%), Dog (91%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CA44 antibody COL4A4 antibody collagen alpha-4(IV) chain antibody "collagen of basement membrane alpha-4 chain antibody" "Collagen IV alpha-4 polypeptide antibody" "collagen type IV alpha 4 antibody" |
|---|---|
| Target | Collagen alpha-4(IV) |
| Molecular Weight(MW) | 164 kDa (note) |
| Cellular Localization | Secreted , extracellular space , extracellular matrix , basement membrane |
| Positive Control | Target recombinant protein |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
