Rabbit Polyclonal antibody to COMP (cartilage oligomeric matrix protein)The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human COMP. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Predicted Reactivity
Human, Mouse, Rat, Zebrafish, Chimpanzee, BovineHuman (100%), Mouse (97%), Rat (97%), Zebrafish (89%), Chimpanzee (100%), Bovine (97%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)