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CRK antibody

Catalog Number:OM248262
OM248262
Discount Price
OM248262-100ul
1~2 Week
100ul
OM248262-50ul
50ul
OM248262-20ul
20ul
1~2 Week
Product Profile
Product Name CRK antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to CRKThis gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008]
Immunogen Recombinant protein of human CRK
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCIHC-PWB
WB: 1:500 - 1:2000, IHC: 1:50 - 1:200:
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms p38
CRKII
v-crk avian sarcoma virus CT10 oncogene homolog
Target CRK
Application

Application

Western blot analysis of extracts of various cells, using CRK antibody.

Application

Immunohistochemistry of paraffin-embedded human liver cancer using CRK antibody at dilution of 1:200 (400x lens).
Application Notes WB: 1:500 - 1:2000, IHC: 1:50 - 1:200:
Additional Information
Form Liquid
Storage Instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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