Application
Sample (50 ug of whole cell lysate) A: Mouse brain 12% SDS PAGE diluted at 1:1000Application
Western Blot analysis of KCNIP3 expression in transfected 293T cell line by KCNIP3 polyclonal antibody. A: Non-transfected lysate. B: KCNIP3 transfected lysate. 12% SDS PAGE diluted at 1:500| Product Name | CSEN antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CSEN (Kv channel interacting protein 3, calsenilin)This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human CSEN. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | HumanMouse |
| Predicted Reactivity | Rat, Rhesus Monkey, BovineRat (94%), Rhesus Monkey (98%), Bovine (94%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CSEN antibody, DREAM antibody, KCHIP3 antibody, MGC18289 antibody, KCNIP3 antibody, kv channel-interacting protein 3 antibody, potassium channel interacting protein 3 antibody, calsenilin antibody, "calsenilin, presenilin-binding protein, EF hand transcrip |
|---|---|
| Molecular Weight(MW) | 29 kDa (note) |
| Cellular Localization | Cytoplasm , Cell membrane; Lipid-anchor , Endoplasmic reticulum , Golgi apparatus , Nucleus , Cytoplasm , Cell membrane , Endoplasmic reticulum , Golgi apparatus , Nucleus |
Application
Sample (50 ug of whole cell lysate) A: Mouse brain 12% SDS PAGE diluted at 1:1000
Application
Western Blot analysis of KCNIP3 expression in transfected 293T cell line by KCNIP3 polyclonal antibody. A: Non-transfected lysate. B: KCNIP3 transfected lysate. 12% SDS PAGE diluted at 1:500| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
