Rabbit Polyclonal antibody to CSN6 (COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis))The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human CSN6. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Zebrafish, Xenopus laevis, Pig, BovineMouse (100%), Rat (100%), Zebrafish (91%), Xenopus laevis (93%), Pig (100%), Bovine (100%)