Application
ChIP analysis of HCT116 cells using CTNNB1 antibody. Cells were prepared using the Farnham ChIP protocol. Use 2μg antibody CTNNB1 antibody for ChIP assay.Application
WB analysis of human fetal heart tissue using CTNNB1 antibody at 0.2-1μg/ml.Application
WB analysis of HCT116 cells using CTNNB1 antibody at 1:1000.| Product Name | CTNNB1 antibody, Internal |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CTNNB1The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009] |
| Immunogen | A synthetic peptide corresponding to an Internal region of Human CTNNB1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBChIP |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Zebrafish: 100% |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CTNNB CTNNB1 ARMADILLO MRD19 |
|---|---|
| Target | CTNNB1 |
| Molecular Weight(MW) | 85 KDa (note) |
Application
ChIP analysis of HCT116 cells using CTNNB1 antibody. Cells were prepared using the Farnham ChIP protocol. Use 2μg antibody CTNNB1 antibody for ChIP assay.
Application
WB analysis of human fetal heart tissue using CTNNB1 antibody at 0.2-1μg/ml.
Application
WB analysis of HCT116 cells using CTNNB1 antibody at 1:1000.| Positive Control | HCT116 , human fetal heart |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
