Application
Western blot analysis of CTRP1 in MDA-MD-361 cell lysate with CTRP1 (IN) antibody at (A) 1 and (B) 2 ug/ml.| Product Name | CTRP1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to CTRP1Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-?-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice (3). |
| Immunogen | Human CTRP1 / G protein coupled receptor interacting protein 1 / GIP (Intermediate Domain) Peptide |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CTRP1 G protein coupled receptor interacting protein1 / GIP G protein coupled receptor interacting protein 1 / GIP |
|---|---|
| Target | CTRP1 |
| Tissue Specificity | This antibody is specific for CTRP1 |
Application
Western blot analysis of CTRP1 in MDA-MD-361 cell lysate with CTRP1 (IN) antibody at (A) 1 and (B) 2 ug/ml.| Positive Control | Blocking Peptide: Cat. No. GTX85080-PEP - CTRP1 Peptide Lysates: Cat. No. GTX23953 - MDA-MB-361 Cell Lysate |
|---|---|
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Antibody is supplied in PBS containing 0.02% sodium azide |
