Rabbit polyclonal to CX3CL1CX3CL1, also known as fractalkine and neurotactin, is a membrane bound CX3C chemokine. The mature protein is part of a 397 amino acid precursor and consists of a chemokine domain of 76 amino acids, a mucin stalk of 241 amino acids, a putative transmembrane domain of 18 amino acids, and an intracellular tail of 37 amino acids. Within the chemokine domain the first two cysteine residues are separated by 3 amino acids (CX3C). CX3CL1 message is found in high abundance in the brain, kidney, lung and heart tissues. CX3CL1 is chemotactic for monocytes and other leukocytes including NK cells, lymphocytes, and may play a role in brain inflammation.
Immunogen
Recombinant fragment - amino acids 379-397 of human CX3CL1 (fractalkine)
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
For WB: Use at a dilution of 1:1,500 - 1:2,500. Optimal dilutions/concentrations should be determined by the researcher.:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)