Application
Human Renal Cell Carcinoma stained with anti-Cyclin D1 antibodyApplication
Human Prostate Adenocarcinoma stained with anti-Cyclin D1 antibodyApplication
Human Pancreatic Adenocarcinoma stained with anti-Cyclin D1 antibodyApplication
Human Ovarian Adenocarcinoma stained with anti-Cyclin D1 antibodyApplication
Human Lung Adenocarcinoma stained with anti-Cyclin D1 antibodyApplication
Human HK Lymphoma stained with anti-Cyclin D1 antibodyApplication
Human B Cell Lymphoma stained with anti-Cyclin D1 antibodyApplication
Human Mantle Cell Lymphoma stained with anti-Cyclin D1 antibodyApplication
Human Tonsil stained with anti-Cyclin D1 antibodyApplication
Human Endometrial Adenocarcinoma stained with anti-Cyclin D1 antibodyApplication
Western Blot analysis of MCF7 cell lysate with Cyclin D1 antibody| Product Name | Cyclin D1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit monoclonal [SP4] to Cyclin D1During each cell cycle cyclins undergo periodic accumulation and destruction. As key regulators of the cell cycle the cyclins control important transitions by acting as regulatory subunits of the Cdks. Early in the G1 phase of the cell cycle, cyclin D1 induction is followed by cyclin E induction. This sequential progression is marked early on in G1 by the activation of Cdk4 and in mid to late G1 by the activation of Cdk2 and the hyperphosphorylation of pRB. The final transition into S phase is thought to be dependent on the increased expression and association of cyclin E and Cdk2.In a recent study, Cyclin D1 regulates cellular metabolism, fat cell differentiation and cellular migration. Cyclin D1 is also involved in development and cancer. |
| Immunogen | Synthetic peptide (Human) (C terminal). |
| Conjugation | Agarose |
| Modification | Acetylated |
| Clonality | Monoclonal |
|---|---|
| Isotype | Cocktail |
| Clone Number | SP4 |
| Host Species | Rabbit |
| Tested Applications | IHCIHC-PWB |
| WB:1:500~1:2000 IHC:1:50~1:200 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Gene Synonyms | P24385 PRAD1 CCND1 BCL1 D11S287E Cyclin D1 U21B31 595 151400 |
|---|---|
| Target | Cyclin D1 |
| Molecular Weight(MW) | 33 kDa |
| Cellular Localization | Nuclear |
Application
Human Renal Cell Carcinoma stained with anti-Cyclin D1 antibody
Application
Human Prostate Adenocarcinoma stained with anti-Cyclin D1 antibody
Application
Human Pancreatic Adenocarcinoma stained with anti-Cyclin D1 antibody
Application
Human Ovarian Adenocarcinoma stained with anti-Cyclin D1 antibody
Application
Human Lung Adenocarcinoma stained with anti-Cyclin D1 antibody
Application
Human HK Lymphoma stained with anti-Cyclin D1 antibody
Application
Human B Cell Lymphoma stained with anti-Cyclin D1 antibody
Application
Human Mantle Cell Lymphoma stained with anti-Cyclin D1 antibody
Application
Human Tonsil stained with anti-Cyclin D1 antibody
Application
Human Endometrial Adenocarcinoma stained with anti-Cyclin D1 antibody
Application
Western Blot analysis of MCF7 cell lysate with Cyclin D1 antibody| Positive Control | Breast carcinomas |
|---|---|
| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.1% Sodium Azide |
