| Product Name | CYP1A2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Cytochrome P450 1A2This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008] |
| Immunogen | Purified human Cytochrome P450 1A2 expressed in E.Coli |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBFunctional Assay |
| Functional Assays: Max Dilution 1-20ul: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Serum |
| Gene Synonyms | CYP1A2 CP12 P450(PA) P3-450 |
|---|---|
| Target | CYP1A2 |
| Tissue Specificity | This antibody recognizes human cytochrome p450 1A2 (CYP1A2). |
| Application Notes | Functional Assays: Max Dilution 1-20ul: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C. Ship at +4°CThis product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
