| Product Name | CYP7A1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to CYP7A1 (cytochrome P450, family 7, subfamily A, polypeptide 1)This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human CYP7A1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Predicted Reactivity | Human, Mouse, Rat, Pig, Rabbit, Rhesus Monkey, BovineHuman (100%), Mouse (83%), Rat (82%), Pig (85%), Rabbit (83%), Rhesus Monkey (94%), Bovine (88%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | CP7A antibody CYP7 antibody CYPVII antibody MGC126826 antibody MGC138389 antibody CYP7A1 antibody cytochrome P450 7A1 antibody "cytochrome P450 subfamily VIIA polypeptide 1 antibody" cholesterol 7-alpha-monooxygenase antibody cholesterol 7-alpha- |
|---|---|
| Target | CYP7A1 |
| Molecular Weight(MW) | 58 kDa (note) |
| Cellular Localization | Endoplasmic reticulum membrane , Microsome membrane |
| Positive Control | Target recombinant protein |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
