Rabbit polyclonal antibody to Cyr61Cyr61 is a member of angiogenic and vasculogenic regulators designated CCN proteins, which includes CTGF, Cyr61 homolog, Fisp2. Cyr61 functions as an angiogenic inducer, stimulating cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells. Elevated expression of Cyr61 is observed during vessel growth, wound healing and chondrocyte differentiation.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate and mouse small intestine tissue lysate can be used as positive controls. The antibody detects the full length and cleaved form of Cyr61 protein from samples of human, mouse and rat origins. Cross-reactivity to other species has not been determined.:
Species Reactivity
HumanMouseRat
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
IGFBP10 O00622 CCN1 602369 CYR61 GIG1
Target
Cyr61
Tissue Specificity
This antibody is specific for Cyr61.
Application
Application
Western blots analysis of Cyr 61 expression with lysate from Jurkat cells (Lane 1) and mouse small intestine tissue(Lane 2).
Application Notes
Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate and mouse small intestine tissue lysate can be used as positive controls. The antibody detects the full length and cleaved form of Cyr61 protein from samples of human, mouse and rat origins. Cross-reactivity to other species has not been determined.:
Additional Information
Form
Liquid
Storage Instructions
The antibody solution should be gently mixed before use. Stored at -20 °C for future use.