Rabbit polyclonal to Cytokeratin 14 predilutedKeratin 14 is a member of the keratin family, the most diverse group of intermediate filaments. It is usually found as a heterotetramer with two molecules of keratin 5, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. Keratin 14 has been studied as a prognostic marker in breast cancer.
Immunogen
Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) C terminal (Human).
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCIHC-P
IHC-P: Prediluted, ready-to-use for 10 min at RT. Staining of formalin-fixed tissues requires digesting tissue sections with pepsin for 10 min at 37C. Optimal dilutions/concentrations should be determined by the end user.:
Human skin stained with anti-cytokeratin 14 antibody, by Immunohistochemistry (FFPE-sections).
Positive Control
A431 cells, Skin or Squamous cell carcinoma
Application Notes
IHC-P: Prediluted, ready-to-use for 10 min at RT. Staining of formalin-fixed tissues requires digesting tissue sections with pepsin for 10 min at 37C. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution and store at 4°C. Do not freeze.
Storage Buffer
PBS, pH 7.4 containing 1%BSA and 0.1% sodium azide