Application
Western blot analysis of Cytokeratin 8 (pS73) expression in HeLa (A); NIH3T3 (B); H9C2 (C) whole cell lysates.| Product Name | Cytokeratin 8 (phospho Ser73) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Cytokeratin 8 (phospho Ser73)This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Cytokeratin 8. The exact sequence is proprietary. |
| Modification | p-Ser73 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | K2C8 CYK8 keratin 8 type II CARD2 KRT8 CK-8 CK8 K8 KO |
|---|---|
| Target | Cytokeratin 8 (phospho Ser73) |
| Tissue Specificity | Recognizes endogenous levels of Cytokeratin 8 (pS73) protein. |
Application
Western blot analysis of Cytokeratin 8 (pS73) expression in HeLa (A); NIH3T3 (B); H9C2 (C) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide. |
