Application
Human Placenta stained with anti-D4-GDI antibodyApplication
staining D4 GDI in human tonsil by Immunohistochemistry (FFPE-sections).| Product Name | D4 GDI antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to D4 GDID4 GDI belongs to the family of Rho GDIs or GDP dissociation inhibitors for the Rho/Rac family of small G proteins; consisting of RhoGDI 1, D4 GDI/RhoGDI2 and Rho GDI3. It inhibits the release of GDP from the Rho proteins, essential for GTP loading and activation of GTPase activity. D4 GDI is located in the cytoplasm and in involved in the regulation of the membrane association and dissociation cycle of Rho/Rac proteins. It is known to be a substrate for caspase 3 during Fas mediated apoptosis. |
| Immunogen | Recombinant full length protein (Human). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| IHC-P: Use at a dilution of 1/100 for 10 min at RT. Boil tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. WB: Use at a concentration of 1 μg/ml for 2hours. Predicted molecular weight: 23 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Ly-GDI D4 GDI 602843 397 P52566 RAP1GN1 GDIA2 D4 LyGDI ARHGDIB GDID4 Ly GDI |
|---|---|
| Target | D4 GDI |
| Cellular Localization | Cytoplasmic and Nuclear |
Application
Human Placenta stained with anti-D4-GDI antibody
Application
staining D4 GDI in human tonsil by Immunohistochemistry (FFPE-sections).| Positive Control | Placenta and tonsil |
|---|---|
| Application Notes | IHC-P: Use at a dilution of 1/100 for 10 min at RT. Boil tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. WB: Use at a concentration of 1 μg/ml for 2hours. Predicted molecular weight: 23 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | Phosphate-buffered saline, pH 7.4 containing 1% BSA and 0.09% sodium azide |
