Rabbit polyclonal antibody to DLGAP5Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.
Immunogen
The antiserum was produced against synthesized peptide derived from human DLGAP5.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
ELISA: 1:40000Optimal dilutions should be determined experimentally by the end user.:
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
hepatoma up-regulated protein hepatoma upregulated protein disks largeassociated protein DLG7 disks large-associated protein DLG7 DLGAP5 HURP hepatoma up regulated protein
Target
DLGAP5
Molecular Weight(MW)
95 kDa (note)
Tissue Specificity
DLGAP5 Antibody detects endogenous levels of total DLGAP5 protein.
Cellular Localization
Localizes to the spindle in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells.
Application
Application
Western blot analysis of extracts from A549/293/HuvEc cells, using DLGAP5 Antibody. The lane on the right is treated with the synthesized peptide.
Application Notes
ELISA: 1:40000Optimal dilutions should be determined experimentally by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at -20 degrees Celcius. Product is stable for at least 1 year.
Storage Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.