Application
Sample (30 ug of whole cell lysate) A: Raji 10% SDS PAGE diluted at 1:1000Application
Immunohistochemical analysis of paraffin-embedded H661 xenograft, using DOK1 antibody at 1:500 dilution.| Product Name | DOK1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to DOK1 (docking protein 1, 62kDa (downstream of tyrosine kinase 1))Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human DOK1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | MGC117395 antibody MGC138860 antibody P62DOK antibody DOK1 antibody Downstream of tyrosine kinase 1 antibody docking protein 1 (downstream of tyrosine kinase 1) antibody pp62 antibody docking protein 1 antibody p62(dok) antibody "docking protein 1 |
|---|---|
| Molecular Weight(MW) | 52 kDa (note) (2) |
Application
Sample (30 ug of whole cell lysate) A: Raji 10% SDS PAGE diluted at 1:1000
Application
Immunohistochemical analysis of paraffin-embedded H661 xenograft, using DOK1 antibody at 1:500 dilution.| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
