Rabbit Polyclonal antibody to Dopamine Receptor D4This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic peptide of human DRD4
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
WB: 1:500 - 1:1000. IHC: 1:50 - 1:100:
Species Reactivity
HumanMonkeyMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
D4DR DRD4 dopamine receptor D4
Molecular Weight(MW)
48 kDa (note)
Application
Application
WB analysis of mouse liver extract using Dopamine Receptor D4 antibody.
Application
IHC-P analysis of human cervical cancer tissue using Dopamine Receptor D4 antibody.
Application Notes
WB: 1:500 - 1:1000. IHC: 1:50 - 1:100:
Additional Information
Form
Liquid
Storage Instructions
Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.