Application
Western Blot detection of Flag-DPP10 in transfected CHO cells with anti-DPP10 antibody at a 1:1000 dilution. The expected MW is 75 kDa; however, oligomerization and differential glycosylation produces other bands as observed with other DPP family members.| Product Name | DPP10 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Anti-DPP10 Polyclonal AntibodyA novel gene, DPP10, encodes a homolog of dipeptidyl peptidases (DPPs) that cleave terminal dipeptides from cytokines and chemokines, and it presents a potential new target for asthma therapy. The DPP10 protein shares features with members of the S9B family of DPP serine proteases, which includes DPP4, a widely expressed enzyme that plays a central role in chemokine processing as part of the innate immune system. The locus displays a complex pattern of transcript splicing, with eight alternate first exons; four of which localize within the LD block strongly associated with asthma. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Recommended dilution for Western blot 1:500-1:1,000. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.: |
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| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | DPL2 DPRP3 DPP10 Q8N608 57628 608209 DPPY |
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Application
Western Blot detection of Flag-DPP10 in transfected CHO cells with anti-DPP10 antibody at a 1:1000 dilution. The expected MW is 75 kDa; however, oligomerization and differential glycosylation produces other bands as observed with other DPP family members.| Application Notes | Recommended dilution for Western blot 1:500-1:1,000. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.: |
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| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | PBS, pH7.2 with 0.02% sodium azide as preservative. |
