| Product Name | DR5 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to DR5TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines. A distinct receptor for TRAIL, TRAIL-R2, by ligand-based affinity purification and subsequent molecular cloning. TRAIL-R2 is widely expressed and the gene encoding TRAIL-R2 is located on human chromosome 8p22-21. TRAIL-R2 engages a caspase-dependent apoptotic pathway but, in contrast to TRAIL-R1, TRAIL-R2 mediates apoptosis via the intracellular adaptor molecule FADD/MORT1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| Not tested. The investigator should determine the optimal dilution for a specific application such as immunohistochemistry.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Serum |
| Gene Synonyms | TNFRSF10B KILLER/DR5 8795 TRICK2 O14763 TRAILR2 KILLER TRICK2A TRICKB 275355 DR5 TRAIL-R2 ZTNFR9 TRICK2B TRAIL R2 CD262 |
|---|
| Application Notes | Not tested. The investigator should determine the optimal dilution for a specific application such as immunohistochemistry.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | 100 µl serum containing 0.02% sodium azide. |
