Application
Western blot analysis of extracts of various tissues, using DUSP6 antibody.Application
Immunohistochemistry of paraffin-embedded human kidney cancer using DUSP6 antibody at dilution of 1:200 (400x lens).Application
Immunohistochemistry of paraffin-embedded human ovarian cancer tissue using DUSP6 antibody.| Product Name | DUSP6 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to DUSP6The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in this gene have been associated with congenital hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014] |
| Immunogen | Recombinant protein of human DUSP6 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCIHC-PWB |
| WB 1:500 - 1:2000, IHC 1:50 - 1:100: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | PYST1 HH19 MKP3 dual specificity phosphatase 6 |
|---|---|
| Molecular Weight(MW) | 42 kDa (note) |
Application
Western blot analysis of extracts of various tissues, using DUSP6 antibody.
Application
Immunohistochemistry of paraffin-embedded human kidney cancer using DUSP6 antibody at dilution of 1:200 (400x lens).
Application
Immunohistochemistry of paraffin-embedded human ovarian cancer tissue using DUSP6 antibody.| Application Notes | WB 1:500 - 1:2000, IHC 1:50 - 1:100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
