Rabbit Polyclonal antibody to EDG1The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. [provided by RefSeq, Jul 2008]
Immunogen
S1P1 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of the human S1P1.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIHC-PWB
IHC-P: 5 ug/mL:
Species Reactivity
Mouse
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
At least two isoforms of S1P1 are known to exist; this S1P1 antibody will only recognize the shorter isoform.
Application
Application
Immunohistochemistry of S1P1 in mouse thymus tissue with S1P1 antibody at 5 ug/mL.
Application
Western blot analysis of S1P1 in mouse thymus lysate with S1P1 antibody at (A) 1 and (B) 2 ug/mL.
Application Notes
IHC-P: 5 ug/mL:
Additional Information
Form
Liquid
Storage Instructions
Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.