Rabbit polyclonal to EDG1EDG1, a Lysophospholipid/Lysosphingolipid Receptor, binds sphingosine-1-phosphate and may control cell proliferation, survival, and suppression of apoptosis. Overexpression of EDG1 leads to increased cell-cell aggregation and overexpression of cadherins. EDG1 transcripts have been reported to be present in embryonic and adult brain, lung alveolar macrophages, vascular smooth muscle cells, endothelial cells, fibroblasts, melanocytes, and TAg-Jurkat T cells, but to be absent from breast cancer cell lines.
Immunogen
Synthetic peptide: SHPQKDDGDNPETI, corresponding to amino acids 359-372 of Mouse EDG1.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ICC/IFIHCIPWB
ICC/IF: 5 ug/ml:
Species Reactivity
HumanMouse
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)