Rabbit Polyclonal antibody to EEDThis gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Immunogen
EED antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human EED.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAICC/IFWB
IF: 20 ug/mL:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
HEED WAIT1 embryonic ectoderm development
Target
EED
Tissue Specificity
Four alternatively spliced transcript variants have been observed.
Application
Application
Immunofluorescence of EED in human heart tissue with EED antibody at 20 ug/mL.
Application
Western blot analysis of EED in human heart tissue lysate with Eed antibody at 1 ug/mL.
Application Notes
IF: 20 ug/mL:
Additional Information
Form
Liquid
Storage Instructions
Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.