Application
Western blot analysis of EGFR (pT678) expression in A431 EGF-treated (A); NIH3T3 EGF-treated (B); PC12 EGF-treated (C) whole cell lysates.| Product Name | EGFR (phospho Thr678) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to EGFR (phospho Thr678)The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human EGFR (pT678). The exact sequence is proprietary. |
| Modification | p-Thr678 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | mENA NISBD2 EGFR HER1 epidermal growth factor receptor PIG61 ERBB1 ERBB |
|---|---|
| Target | EGFR (phospho Thr678) |
| Tissue Specificity | Recognizes endogenous levels of EGFR (pT678) protein. |
Application
Western blot analysis of EGFR (pT678) expression in A431 EGF-treated (A); NIH3T3 EGF-treated (B); PC12 EGF-treated (C) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide. |
