Application
Peptide Block–EGFR [pY1173] ELISA.| Product Name | EGFR (phospho Tyr1173) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to EGFR ( phospho Y1173 )EGFR is the prototype member of the type 1 receptor tyrosine kinases. EGFR is encoded by the cellular oncogene c-erbB-1. EGFR has an extracellular ligand binding domain, a single transmembrane region, and cytoplasmic domain which is composed of a tyrosine kinase domain and a carboxy terminal domain. The carboxy terminal domain contains at least four tyrosine autophosphorylation sites. EGFR over-expression in tumors indicates poor prognosis. EGFR over-expression is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma. |
| Immunogen | Synthetic phosphopeptide (Human) derived from the region of EGFR that contains tyrosine 1173. |
| Modification | p-Tyr1173 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| WB: Use at a concentration of 0.1 - 1.0 μg/ml. Detects a band of approximately 185 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ERBB1 131550 1956 EGFR ERBB mENA P00533 EGFR (phospho Y1173) EGFR (phospho Tyr1173) EGFR (pY1173) EGFR (pTyr1173) EGFR phospho Y1173 EGFR phospho Tyr1173 Phospho EGFR (Y1173) Phospho EGFR (Tyr1173) Phospho EGFR (pY1173) Phospho EGFR (pTyr1 |
|---|---|
| Target | EGFR |
| Cellular Localization | Cell Membrane and Secreted |
Application
Peptide Block–EGFR [pY1173] ELISA.| Positive Control | NIH3T3 cells expressing human EGFR |
|---|---|
| Application Notes | WB: Use at a concentration of 0.1 - 1.0 μg/ml. Detects a band of approximately 185 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.05% Sodium Azide; Constituents: PBS, 50% glycerol,1mg/ml BSA. pH 7.3 |
