Application
Western blot analysis of EPO Receptor (pY426) expression in A498 (A); MCF7 pervanadate-treated (B); NIH3T3 (C) whole cell lysates.| Product Name | EPO Receptor (phospho Tyr426) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to EPO Receptor (phospho Tyr426)This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human EPO Receptor. The exact sequence is proprietary. |
| Modification | p-Tyr426 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | EPOR erythropoietin receptor EPO-R |
|---|---|
| Target | EPO Receptor (phospho Tyr426) |
| Tissue Specificity | Recognizes endogenous levels of EPO Receptor (pY426) protein. |
Application
Western blot analysis of EPO Receptor (pY426) expression in A498 (A); MCF7 pervanadate-treated (B); NIH3T3 (C) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide. |
