Application
Western blot analysis of Focal Adhesion Kinase (pY861) expression in HUVEC (A); HeLa (B) whole cell lysates.| Product Name | FAK (phospho Tyr861) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to FAK (phospho Tyr861)This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq, Dec 2010] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Focal Adhesion Kinase. The exact sequence is proprietary. |
| Modification | p-Tyr861 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | FADK PPP1R71 FAK p125FAK pp125FAK PTK2 protein tyrosine kinase 2 FRNK FAK1 |
|---|---|
| Target | FAK (phospho Tyr861) |
| Tissue Specificity | Recognizes endogenous levels of Focal Adhesion Kinase (pY861) protein. |
Application
Western blot analysis of Focal Adhesion Kinase (pY861) expression in HUVEC (A); HeLa (B) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide. |
