Rabbit Polyclonal antibody to FHITThis gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
Immunogen
FHIT antibody was raised against an 18 amino acid peptide near the carboxy terminus of human FHIT.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAICC/IFWB
WB: 1 - 2 ug/ml:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
AP3Aase fragile histidine triad FRA3B
Target
FHIT
Tissue Specificity
FHIT antibody is human specific.
Application
Application
Immunofluorescence of FHIT in HeLa cells with FHIT antibody at 5 ug/mL.
Application
Western blot analysis of FHIT in HeLa cell lysate with FHIT antibody at (A) 1 and (B) 2 ug/ml.
Application Notes
WB: 1 - 2 ug/ml:
Additional Information
Form
Liquid
Storage Instructions
Be stored at 4oC for three months and -20oC, stable for up to one year.