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FKBP1B antibody, N-term

Catalog Number:OM253226
OM253226
Discount Price
OM253226-100ul
1~2 Week
100ul
OM253226-50ul
50ul
OM253226-20ul
20ul
1~2 Week
Product Profile
Product Name FKBP1B antibody, N-term
Antibody Type Primary Antibodies
Product description

Rabbit polyclonal to FKBP1B (N-term)The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK56 and rapamycin. It is highly similar to the FK56-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq]

Immunogen The immunogen corresponding to a region within amino acids 16 and 46 of human FKBP1B.
Conjugation Agarose
Modification Acetylated
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ICC/IFIHC-PWB
WB:1:500~1:2000
IHC-P:1:50~1:200
ICC/IF:1:50~1:100
Species Reactivity HumanMouse
Concentration 1mg/ml
Target Information
Gene Synonyms Peptidylprolyl cistrans isome
FKBP-1B
Peptidyl-prolyl cis-trans isomerase FKBP1B
FKBP1B
FKBP1L
FKBP12.6
Immunophilin FKBP12.6
12.6 kDa FKBP
FKBP9
FK506-binding protein 1B
FK506binding protein1B
hFKBP12
Peptidylprolyl cistrans isomerase FKBP1B
Target FKBP1B
Molecular Weight(MW) 11.783 kDa (note)
Application

Application

Western blot analysis of FKBP1B antibody (N-term) in mouse cerebellum tissue lysates (35ug/lane). FKBP1B (arrow) was detected using the purified Pab.

Application

Confocal immunofluorescent analysis of FKBP1B Antibody (N-term) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Application

Western blot analysis of FKBP1B antibody (N-term) in 293 cell line lysates (35ug/lane). FKBP1B (arrow) was detected using the purified Pab.

Application

FKBP1B Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FKBP1B Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

WB

b Western blot showing calstabin2 protein levels in the LA of naive mice, shRNA-NC infected mice, and calstabin2 KD mice. Left: representative Western blot. Right: calstabin2 expression histograms. The y-axis indicates the calstabin2 protein expression level for each condition relative to naive control. The calstabin2 protein level for each condition was normalized to the BMP level. N = 3 for each group. Statistics, One-way ANOVA and Bonferroni post-hoc test. ***p < 0.001 compared with naive and shRNA-NC groups.
Application Notes WB:1:500~1:2000
IHC-P:1:50~1:200
ICC/IF:1:50~1:100
Additional Information
Form Liquid
Storage Instructions Store at at 2-8°C for up to 6 months. For long term storage, aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.09% (W/V) sodium azide
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