Rabbit polyclonal antibody to FMO2 (flavin containing monooxygenase 2 (non-functional))The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in humans, this enzyme is truncated and is probably rapidly degraded. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human FMO2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
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Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Rabbit, Rhesus Monkey, Chimpanzee, BovineMouse (83%), Rat (82%), Rabbit (84%), Rhesus Monkey (96%), Chimpanzee (99%), Bovine (81%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)