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Folate receptor beta antibody

Catalog Number:OM253397
OM253397
Discount Price
OM253397-100ul
1~2 Week
100ul
OM253397-50ul
50ul
OM253397-20ul
20ul
1~2 Week
Product Profile
Product Name Folate receptor beta antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to Folate receptor beta (folate receptor 2 (fetal))The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq]
Immunogen Recombinant protein encompassing a sequence within the center region of human Folate receptor beta. The exact sequence is proprietary.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ICC/IFIHCIHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity HumanMouse
Predicted Reactivity Rat, Rhesus Monkey, BovineRat (84%), Rhesus Monkey (97%), Bovine (86%)
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified
Target Information
Gene Synonyms FR-P3
folate receptor 2 (fetal)
FBP/PL-1
FOLR2
FBP
FR-BETA
BETA-HFR
Target Folate receptor beta
Molecular Weight(MW) 29 kDa (note) (4)
Cellular Localization Cell membrane; Lipid-anchor , GPI-anchor , Secreted
Application

Application

Folate receptor beta antibody detects Folate receptor beta protein at membrane on mouse prostate by immunohistochemical analysis. Sample: Paraffin-embedded mouse prostate. Folate receptor beta antibody dilution: 1:500.

Application

Folate receptor beta antibody detects Folate receptor beta protein by western blot analysis. Various whole cell extracts (30 µg) were separated by 12% SDS-PAGE, and the membrane was blotted with Folate receptor beta antibody diluted by 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Positive Control Jurkat , Raji , NCI-H929
Application Notes *Optimal dilutions/concentrations should be determined by the researcher. :
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
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