Rabbit Polyclonal antibody to FOXO4 (phospho Thr451)This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human FOXO4. The exact sequence is proprietary.
Modification
p-Thr451
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: 1:500 - 1:1000:
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
FOXO4 AFX forkhead box O4 AFX1 MLLT7
Target
FOXO4 (phospho Thr451)
Tissue Specificity
Recognizes endogenous levels of FOXO4 (pT451) protein.
Application
Application
Western blot analysis of FOXO4 (pT451) expression in THP1 EGF-treated (A); K562 (B); Jurkat (C); NIH3T3 (D); mouse lung (E) whole cell lysates.
Application Notes
WB: 1:500 - 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.