Rabbit Polyclonal antibody to Frizzled 6 (frizzled family receptor 6)Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD6 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and 7 transmembrane domains. However, unlike many other Fz family members, FDZ6 does not contain a C-terminal PDZ domain-binding motif. [provided by RefSeq]
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Frizzled 6. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Rhesus MonkeyRhesus Monkey (100%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
NDNC10 FZD6 HFZ6 FZ-6 FZ6 frizzled family receptor 6
Target
Frizzled 6
Molecular Weight(MW)
79 kDa (note) (3)
Cellular Localization
Membrane; Multi-pass membrane protein
Application
Application
Various cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Frizzled 6 antibody diluted at 1:1000.