Application
WB analysis of MCF-7 cells using G6PC antibody at 1μg/ml.Application
IHC-P analysis of human kidney tissue using G6PC antibody at 5μg/ml.Application
WB analysis of human fetal lung tissue using G6PC antibody at 1μg/ml.| Product Name | G6PC antibody, N-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to G6PCGlucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.[provided by RefSeq, Feb 2011] |
| Immunogen | A synthetic peptide corresponding to a N-terminal region of Human G6PC |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
|
| Species Reactivity | Human |
| Predicted Reactivity | Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 93%; Rat: 93%; Sheep: 100% |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | G6PC GSD1A G6PT GSD1 G6PC1 |
|---|---|
| Target | G6PC |
| Molecular Weight(MW) | 40 KDa (note) |
Application
WB analysis of MCF-7 cells using G6PC antibody at 1μg/ml.
Application
IHC-P analysis of human kidney tissue using G6PC antibody at 5μg/ml.
Application
WB analysis of human fetal lung tissue using G6PC antibody at 1μg/ml.| Positive Control | human fetal lung , MCF-7 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1x PBS buffer with 0.09% (w/v) sodium azide and may contain up to 2% sucrose. |
