Application
GABA A Receptor alpha 1 antibody [N1C1] detects GABA A Receptor alpha 1 protein at cytoplasm in rat brain by immunohistochemical analysis. Sample: Paraffin-embedded rat brain. GABA A Receptor alpha 1 antibody [N1C1] diluted at 1:500.Application
GABA A Receptor alpha 1 antibody detects GABA A Receptor alpha 1 protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with GABA A Receptor alpha 1 antibody diluted by 1:1000.| Product Name | GABA A Receptor alpha 1 antibody |
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| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to GABA A Receptor alpha 1 (gamma-aminobutyric acid (GABA) A receptor, alpha 1)This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human GABA A Receptor alpha 1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
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| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | HumanRat |
| Predicted Reactivity | Mouse, Zebrafish, Rabbit, Chicken, Rhesus Monkey, BovineMouse (99%), Zebrafish (89%), Rabbit (100%), Chicken (97%), Rhesus Monkey (100%), Bovine (100%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ECA4 antibody EJM antibody EJM5 antibody GABRA1 antibody GABA(A) receptor subunit alpha-1 antibody gamma-aminobutyric acid receptor subunit alpha-1 antibody "gamma-aminobutyric acid (GABA) A receptor alpha 1 antibody" |
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| Target | GABA A Receptor alpha 1 |
| Molecular Weight(MW) | 52 kDa (note) (7) |
| Cellular Localization | Cell junction , synapse , postsynaptic cell membrane; Multi-pass membrane protein , Cell membrane; Multi-pass membrane protein |
Application
GABA A Receptor alpha 1 antibody [N1C1] detects GABA A Receptor alpha 1 protein at cytoplasm in rat brain by immunohistochemical analysis. Sample: Paraffin-embedded rat brain. GABA A Receptor alpha 1 antibody [N1C1] diluted at 1:500.
Application
GABA A Receptor alpha 1 antibody detects GABA A Receptor alpha 1 protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with GABA A Receptor alpha 1 antibody diluted by 1:1000.| Positive Control | U87-MG , SK-N-SH |
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| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
