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GABA A Receptor beta 3 antibody

Catalog Number:OM253853
OM253853
Discount Price
OM253853-100ul
1~2 Week
100ul
OM253853-50ul
50ul
OM253853-20ul
20ul
1~2 Week
Product Profile
Product Name GABA A Receptor beta 3 antibody
Antibody Type Primary Antibodies
Product description Rabbit polyclonal antibody to GABA A receptor beta 3GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics. GABA (A) Receptors are comprised of subunits and these are further classified into 3 major groups (alpha, beta, and gamma). The subunits determine the pharmacological characteristics.
Immunogen Fusion protein of MBP with the amino acid sequence representing the cytosolic loop of the rat GABA-A receptor beta 3 subunit.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHC-FWB
We recommend the following starting dilutions: Western Blot 1:1000. Optimal concentration should be determined experimentally by the end user.:
Species Reactivity HumanRatBovine
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms gammaaminobutyric
gamma-aminobutyric acid (GABA) A receptor bet
GABA-A receptor beta-3 subunit
2562 24922
gammaaminobutyric acid (GABA) A receptor bet
GABA A receptor beta3
GABRB3
Gamma aminobutyric acid receptor subunit beta
256224922
GABAA recep
Target GABA A receptor beta 3
Tissue Specificity reacts with the 51-56 kDa beta 3 subunit of rat brain GABA-A. There is no known reactivity with other GABA subunits. There is no homology with other GABA subunits.
Application

Application

Western Blot: GABA A Receptor beta 3 Antibody [ - GABA A receptor beta 3 antibody [

Application

Western Blot: GABA A Receptor beta 3 Antibody [ - 5-7 ug of mouse cerebellum lysates from wild type (Control) and beta 3 knockout (beta 3 K/O) animals showing specific immunolabeling of the ~53k beta 3-subunit of the GABAA-R in the wild type but not in the beta 3 K/O animals.
Application Notes We recommend the following starting dilutions: Western Blot 1:1000. Optimal concentration should be determined experimentally by the end user.:
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Storage Buffer 10mM HEPES [pH7.5] with 150 mM NaCl, 100ug/ml BSA & 50 % glycerol
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