Rabbit Polyclonal antibody to GALNSThis gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant protein of human GALNS
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
WB 1:500 - 1:2000, IHC 1:50 - 1:200:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
MPS4A galactosamine (N-acetyl)-6-sulfatase GalN6S GAS GALNAC6S
Target
GALNS
Molecular Weight(MW)
58 kDa (note)
Application
Application
Western blot analysis of extracts of various cell lines, using GALNS antibody.