Application
Sample(30 ug whole cell lysate) A:A431 12% SDS PAGE diluted at 1:1000| Product Name | gamma C Crystallin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Gamma-crystallin C (crystallin, gamma C)Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human gamma C Crystallin. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Dog, Rhesus Monkey, Chimpanzee, Bovine, Guinea pigMouse (84%), Rat (85%), Dog (87%), Rhesus Monkey (96%), Chimpanzee (99%), Bovine (85%), Guinea pig (86%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | CCL antibody, CRYG3 antibody, CRYGC antibody, gamma-crystallin 2-1 antibody, "crystallin, gamma-3 antibody", gamma-crystallin C antibody, gamma-C-crystallin antibody, gamma-crystallin 3 antibody, "crystallin, gamma C antibody" |
|---|---|
| Target | Gamma-crystallin C |
| Molecular Weight(MW) | 21 kDa (note) |
Application
Sample(30 ug whole cell lysate) A:A431 12% SDS PAGE diluted at 1:1000| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
