Application
Sample (30 ug of whole cell lysate) A: Jurkat 10% SDS PAGE diluted at 1:500Application
Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using GBA3 antibody at 1:250 dilution.| Product Name | GBA3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to GBA3 (glucosidase, beta, acid 3 (cytosolic))GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).[supplied by OMIM] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human GBA3. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Predicted Reactivity | BovineBovine (96%) |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CBGL1 antibody, GLUC antibody, KLrP antibody, MGC104276 antibody, MGC126878 antibody, GBA3 antibody, cytosolic beta-glucosidase-like protein 1 antibody, klotho-related protein antibody, cytosolic beta-glucosidase antibody, "glucosidase, beta, acid 3 (cytos |
|---|---|
| Molecular Weight(MW) | 54 kDa (note) (2) |
| Cellular Localization | Cytoplasm , cytosol |
Application
Sample (30 ug of whole cell lysate) A: Jurkat 10% SDS PAGE diluted at 1:500
Application
Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using GBA3 antibody at 1:250 dilution.| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
