Application
Western blot detection of GLUT4 from rat heart using| Product Name | GLUT4 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to GLUT4The stimulation of glucose uptake by insulin in muscle and adipose tissue requires translocation of the GLUT4 (Glucose transporter type 4, insulin-responsive) glucose transporter from intracellular storage sites to the cell surface. Insulin stimulates glucose transport by promoting translocation of GLUT4 proteins from the perinuclear compartment to the cell surface. Human insulin resistance involves a defect in GLUT4 traffic and targeting leading to accumulation in a dense membrane compartment from which insulin is unable to recruit GLUT4 to the cell surface. |
| Immunogen | Synthetic peptide corresponding to residues E(493) Q E V K P S T E L E Y L G P D E N D(509) of rat GLUT4. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:1000 Optimal dilution / concentration should be determined by the end user.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | Slc2a4 Glut-4 Glut4 solute carrier family 2 (facilitated glucose transporter) member 4 |
|---|---|
| Target | Glucose Transporter 4 |
Application
Western blot detection of GLUT4 from rat heart using| Application Notes | WB: 1:1000 Optimal dilution / concentration should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS containing 1 mg/ml BSA and 0.05% sodium azide. |
